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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9491 | Pyraclostrobin | Antibacterial , Antifungal | |
Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells. | |||
T14557 | BI-1935 | Epoxide Hydrolase | |
BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease. | |||
T9920 | Evolocumab | Others | |
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9). | |||
TN6490 | Regaloside C | Others | |
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties. | |||
T12931 | SLC13A5-IN-1 | Stearoyl-CoA Desaturase (SCD) | |
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells). | |||
T10900 | CUDA | PPAR , Epoxide Hydrolase | |
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR... | |||
T8737 | GR 125743 | 5-HT Receptor | |
GR 125743 is a novel antagonist of 5-HT1B/1D receptor. | |||
T14844 | BX430 | P2X Receptor , Calcium Channel | |
BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity. | |||
T15047 | Dacisteine | N,S-Diacetyl-L-cysteine | Others |
Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM). | |||
T1135 | Vitamin D3 | Cholecalciferol,Colecalciferol | Endogenous Metabolite |
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR). | |||
T10814 | Cinacalcet metabolite M4 | Rarechem AL BW 1078 | Calcium Channel |
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor. | |||
T6595 | Moexipril hydrochloride | Moexipril HCl,RS-10085,SPM 925,CI-925 | Apoptosis , RAAS |
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure. | |||
T23127 | PD-161570 | PD 161570 | EGFR , FGFR , PDGFR , Src |
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a... | |||
T9999 | Sirtuin modulator 2 | N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide | Others , Sirtuin |
Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities. | |||
T32160 | Indolidan | LY 195115 | |
Indolidan (LY 195115) induces cardiovascular and adrenal hyperplastic lesions in Fischer 344 rats. Indolidan increases the risk of cardiovascular disease. | |||
T30191L | Atecegatran TFA | Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA | Others |
Atecegatran TFA is often used as an anticoagulant and can be used to treat cardiovascular disease. | |||
T27357 | FPL-62129 | FPL 62129,FPL62129 | RAAS , Calcium Channel |
FPL-62129 is a calcium channel antagonist and a novel angiotensin-converting enzyme inhibitor with vasodilator activity for the study of cardiovascular disease. | |||
T77648 | Casein kinase 1δ-IN-14 | WAY-637081 | Others |
Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease. | |||
T13154 | Tiapamil hydrochloride | Ro 11-1781 hydrochloride,ORE 5002 hydrochloride | Calcium Channel |
Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity and may be used in the study of angina and cardiovascular disease. | |||
T31611 | Eldacimibe | WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147 | Acyltransferase |
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia. |