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Search Results for " cardiovascular disease "

20

Compounds

Cat No. Product Name Synonyms Targets
T9491 Pyraclostrobin Antibacterial , Antifungal
Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.
T14557 BI-1935 Epoxide Hydrolase
BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease.
T9920 Evolocumab Others
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T12931 SLC13A5-IN-1 Stearoyl-CoA Desaturase (SCD)
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).
T10900 CUDA PPAR , Epoxide Hydrolase
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR...
T8737 GR 125743 5-HT Receptor
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
T14844 BX430 P2X Receptor , Calcium Channel
BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity.
T15047 Dacisteine N,S-Diacetyl-L-cysteine Others
Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).
T1135 Vitamin D3 Cholecalciferol,Colecalciferol Endogenous Metabolite
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
T10814 Cinacalcet metabolite M4 Rarechem AL BW 1078 Calcium Channel
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.
T6595 Moexipril hydrochloride Moexipril HCl,RS-10085,SPM 925,CI-925 Apoptosis , RAAS
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T9999 Sirtuin modulator 2 N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide Others , Sirtuin
Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.
T32160 Indolidan LY 195115
Indolidan (LY 195115) induces cardiovascular and adrenal hyperplastic lesions in Fischer 344 rats. Indolidan increases the risk of cardiovascular disease.
T30191L Atecegatran TFA Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA Others
Atecegatran TFA is often used as an anticoagulant and can be used to treat cardiovascular disease.
T27357 FPL-62129 FPL 62129,FPL62129 RAAS , Calcium Channel
FPL-62129 is a calcium channel antagonist and a novel angiotensin-converting enzyme inhibitor with vasodilator activity for the study of cardiovascular disease.
T77648 Casein kinase 1δ-IN-14 WAY-637081 Others
Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.
T13154 Tiapamil hydrochloride Ro 11-1781 hydrochloride,ORE 5002 hydrochloride Calcium Channel
Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity and may be used in the study of angina and cardiovascular disease.
T31611 Eldacimibe WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147 Acyltransferase
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.
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TargetMol